Laevigatbenzoate from Croton laevigatus Vahl.

被引：0
|
作者：
Guo-An Zou
Hong-Wu Zhang
Haji Akber Aisa
Jun-Shan Yang
Chao-Zhong Peng
Zhong-Mei Zou
机构：
[1] Chinese Academy of Medical Sciences and Peking Union Medical College,Institute of Medicinal Plant Development
[2] Chinese Academy of Sciences,Xinjiang Technical Institute of Physics and Chemistry
来源：
Journal of Natural Medicines | 2011年 / 65卷
关键词：
Vahl.; Euphorbiaceae; Diterpenoid; Laevigatbenzoate; Cytotoxicity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new trans-clerodane diterpenoid, laevigatbenzoate (1), was isolated from the leaves of Croton laevigatus Vahl. Its structure was established on the basis of spectroscopic analysis, and the absolute configuration was determined by application of the CD excitation chirality method. This compound showed weak cytotoxicity against HeLa cells, with an IC50 value of 45.4 μM.
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页码：391 / 394
页数：3
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