In vivo animal models confirm an increased virulence potential and pathogenicity of the NAP1/RT027/ST01 genotype within the Clostridium difficile MLST Clade 2

被引：0

作者：

Josué Orozco-Aguilar

Alejandro Alfaro-Alarcón

Luis Acuña-Amador

Esteban Chaves-Olarte

César Rodríguez

Carlos Quesada-Gómez

机构：

[1] Universidad de Costa Rica,Laboratorio de Ensayos Biológicos (LEBi)

[2] Universidad de Costa Rica,Facultad de Farmacia

[3] Universidad de Costa Rica,Programa de Posgrado en Microbiología, Parasitología, Química Clínica e Inmunología

[4] Universidad Nacional,Departamento de Patología, Escuela de Medicina Veterinaria

[5] Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,undefined

[6] Universidad de Costa Rica,undefined

来源：

Gut Pathogens | / 12卷

关键词：

Pathogenicity; Virulence; MLST Clade 2; NAP1/RT027/ST01;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 266 条

[21]

Aktories K(2010) polymerase chain reaction ribotype 027/toxinotype III in The Netherlands Clin Microbiol Rev 23 529-4911

[22]

Riedel T(2011)Emergence of PLoS ONE 6 e25754-10

[23]

Wittmann J(2012)-associated disease in North America and Europe PLoS ONE 7 e31559-24

[24]

Bunk B(2013)A predominantly clonal multi-institutional outbreak of PLoS Pathog 9 e1003523-498

[25]

Schober I(2018)-associated diarrhea with high morbidity and mortality Anaerobe 53 21-273

[26]

Spröer C(2010)Increased sporulation rate of epidemic J Bacteriol 192 4904-865

[27]

Gronow S(2017) Type 027/NAP1 Sci Rep. 7 1-84

[28]

Ramírez-Vargas G(2013)The relationship between phenotype, ribotype, and clinical disease in human PLoS ONE 8 e78404-941

[29]

López-Ureña D(2016) isolates Anaerobe 37 13-100

[30]

Badilla A(2020)Multilocus sequence typing of Clin Microbiol Infect 26 492-622