Perioperative cell-free DNA trends predict recurrence of non-metastatic colorectal cancer significantly earlier than CEA trends over the first 2 years post-operatively in stage II and stage III colon cancer

[1] Ferlay J(2013)Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012 Eur J Cancer 49 1374-1403

[2] Siegel RL(2019)Cancer statistics, 2019 CA Cancer J Clin 69 7-34

[3] Miller KD(2016)Patterns of metastasis in colon and rectal cancer Sci Rep 6 1-9

[4] Jemal A(2015)Nationwide trends in incidence, treatment and survival of colorectal cancer patients with synchronous metastases Clin Exp Metastasis 32 457-465

[5] Riihimaki M(2017)Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the Management of Cancer of the Colon, Rectum and Anus (2017) – Surgical Management Color Dis 19 18-36

[6] Hemminki A(2014)Predictive factors and the prognosis of recurrence of colorectal cancer within 2 years after curative resection Ann Surg Treat Res 86 143-151

[7] Sundquist J(2019)Follow-up strategies for patients treated for non-metastatic colorectal cancer Cochrane Database Syst Rev 9 2019-1034

[8] Hemminki K(2002)Factors affecting local recurrence of colonic adenocarcinoma Dis Colon Rectum 45 1029-440

[9] van der Geest LGM(2007)Loco-regional recurrence from colon cancer: a population-based study Ann Surg Oncol 14 432-458

[10] Lam-Boer J(2002)The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited Nat Rev Cancer 3 453-70

[1] Ferlay J(2013)Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012 Eur J Cancer 49 1374-1403

[2] Siegel RL(2019)Cancer statistics, 2019 CA Cancer J Clin 69 7-34

[3] Miller KD(2016)Patterns of metastasis in colon and rectal cancer Sci Rep 6 1-9

[4] Jemal A(2015)Nationwide trends in incidence, treatment and survival of colorectal cancer patients with synchronous metastases Clin Exp Metastasis 32 457-465

[5] Riihimaki M(2017)Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the Management of Cancer of the Colon, Rectum and Anus (2017) – Surgical Management Color Dis 19 18-36

[6] Hemminki A(2014)Predictive factors and the prognosis of recurrence of colorectal cancer within 2 years after curative resection Ann Surg Treat Res 86 143-151

[7] Sundquist J(2019)Follow-up strategies for patients treated for non-metastatic colorectal cancer Cochrane Database Syst Rev 9 2019-1034

[8] Hemminki K(2002)Factors affecting local recurrence of colonic adenocarcinoma Dis Colon Rectum 45 1029-440

[9] van der Geest LGM(2007)Loco-regional recurrence from colon cancer: a population-based study Ann Surg Oncol 14 432-458

[10] Lam-Boer J(2002)The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited Nat Rev Cancer 3 453-70