Is Bariatric Surgery Effective in Reducing Comorbidities and Drug Costs? A Systematic Review and Meta-Analysis

被引:0
作者
E. C. Lopes
I. Heineck
G. Athaydes
N. G. Meinhardt
K. E. P. Souto
A. T. Stein
机构
[1] Universidade Federal do Rio Grande do Sul—UFRGS,Programa de Pós Graduação em Epidemiologia, Departamentode Medicina Social, Faculdade de Medicina
[2] Secretaria Estadual de Saúde do Rio Grande do Sul,Public Health School
[3] Universidade Federal do Rio Grande do Sul—UFRGS,Programa de Pós Graduação em Assistência Farmacêutica and Programa de Pós Graduação em Ciências Farmacêuticas, Faculdade de Farmácia
[4] Universidade Federal do Rio Grande do Sul,Faculdade de Farmácia
[5] Nossa Senhora da Conceição Hospital (Hospital Nossa Senhora da Conceição—HNSC),Center for Attendance to Obesity Degree III
[6] Nossa Senhora da Conceição Hospital (Hospital Nossa Senhora da Conceição—HNSC,undefined
[7] Universidade Federal de Ciências da Saúde de Porto Alegre—UFCSPA,undefined
[8] Universidade Luterana do Brasil—ULBRA,undefined
来源
Obesity Surgery | 2015年 / 25卷
关键词
Bariatric surgery; Drug costs; Meta-analysis; Pharmacoepidemiology; Cost analysis;
D O I
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中图分类号
学科分类号
摘要
The aim of this study was to assess drug use and costs before and after bariatric surgery (BS). A systematic review of the literature was carried out using the MeSH terms obesity, bariatric surgery, and drug costs for searches of 10 electronic databases up to July 2014. Data were extracted from the 11 studies (37,720 patients) that fulfilled the inclusion criteria. Where applicable, data were pooled by meta-analysis. The average number of drugs per patient decreased from 3.9 ± 1.86 before surgery to 1.75 ± 1.85 after surgery. Mean reduction in total cost of drugs was 49.8 % over a follow-up duration of 6–72 months. BS is effective for the improvement or resolution of comorbidities and significantly reduces drug use and costs.
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页码:1741 / 1749
页数:8
相关论文
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  • [1] Santos LMP(2010)Trends in morbid obesity and in bariatric surgeries covered by the Brazilian public health system Obes Surg 20 943-8
  • [2] Oliveira IV(2004)Bariatric surgery: shedding the monetary weight of prescription costs in the managed care arena Obes Surg 14 725-30
  • [3] Peters LR(2004)The effect of Roux-en-Y gastric bypass on prescription drug costs Obes Surg 14 1031-5
  • [4] Potteiger CE(2007)Predictive factors of outcome after gastric banding: a nationwide survey on the role of center activity and patients' behavior Ann Surg 246 1034-9
  • [5] Paragi PR(2012)Vitamin, mineral, and drug absorption following bariatric surgery Curr Drug Metab 13 1345-55
  • [6] Inverso NA(2002)Long-term effects of weight loss on pharmaceutical costs in obese subjects. A report from the SOS intervention study Int J Obes Relat Metab Disord 26 184-92
  • [7] Snow LL(2009)The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation Health Technol Assess 13 1-190
  • [8] Weinstein LS(2011)Bariatric surgery: a systematic review of the clinical and economic evidence J Gen Intern Med 26 1183-94
  • [9] Hannon JK(2002)Quantifying heterogeneity in a meta-analysis Stat Med 21 1539-58
  • [10] Chevallier JM(2002)Pharmaceutical costs in obese individuals: comparison with a randomly selected population sample and long-term changes after conventional and surgical treatment: the SOS intervention study Arch Intern Med 162 2061-9