Evaluation and management of syphilis in the HIV-infected patient

被引：11
作者：
Ghanem K.G. [1 ]
机构：
[1] Infectious Diseases Division, Johns Hopkins University, Bayview Medical Center, Baltimore, MD 21224, 4940 Eastern Avenue, B3N
来源：
Current Infectious Disease Reports | 2010年 / 12卷 / 2期
关键词：
Antiretroviral therapy; HAART; HIV; Neurosyphilis; Syphilis;
D O I：
10.1007/s11908-010-0083-6
中图分类号：
学科分类号：
摘要：
Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninfected patients, the former may be at increased risk for complications. Recent data suggest that HIV-induced immunosuppression may alter the course of syphilis and that highly active antiretroviral therapy may have a beneficial effect on syphilis outcomes. Prevention strategies consisting of sexual risk assessments, condom use, treatment of infected partners, yearly screening for syphilis of all HIV-infected patients, and enhanced clinical and serologic follow-up of treated HIV-infected patients are critical components of a comprehensive approach to care. © The Author(s) 2010.
引用
收藏
页码：140 / 146
页数：6
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