Histocompatibility: minor differences have a major impact

被引：0
作者：
Roman Reindl-Schwaighofer
Rainer Oberbauer
机构：
[1] Medical University of Vienna,Division of Nephrology and Dialysis, Department of Internal Medicine III
来源：
Nature Reviews Nephrology | 2019年 / 15卷
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摘要：
The clinical relevance of minor histocompatibility antigens in transplantation is disputed. High-throughput approaches are now being used to investigate the role of genome-wide genetic incompatibility in transplant outcomes. A recent study reports that donor and recipient mismatch at the LIMS1 locus is associated with an increased risk of acute rejection.
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页码：529 / 530
页数：1
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