Brownian-dynamics simulations of protein–protein interactions in the photosynthetic electron transport chain

被引:3
作者
Khruschev S.S. [1 ]
Abaturova A.M. [1 ]
Diakonova A.N. [1 ]
Fedorov V.A. [1 ]
Ustinin D.M. [1 ]
Kovalenko I.B. [1 ]
Riznichenko G.Y. [1 ]
Rubin A.B. [1 ]
机构
[1] Department of Biology, Lomonosov Moscow State University, Moscow
基金
俄罗斯基础研究基金会;
关键词
Brownian dynamics; electron transport; multiparticle computer simulation; photosyn-; thesis; protein–protein interactions;
D O I
10.1134/S0006350915020086
中图分类号
学科分类号
摘要
The application of Brownian dynamics for simulation of transient protein–protein interactions is reviewed. The review focuses on the theoretical basics of the Brownian-dynamics method, its particular implementations, and the advantages and drawbacks of this method. The outlook for future development of Brownian dynamics-based simulation techniques is discussed. Special attention is given to analysis of Brownian dynamics trajectories. The second part of the review is dedicated to the role of Brownian-dynamics simulations in studying photosynthetic electron transport. Interactions of mobile electron carriers (plastocyanin, cytochrome c6, and ferredoxin) with their reaction partners (cytochrome b6f complex, photosystem I, ferredoxin:NADP reductase, and hydrogenase) are considered. © 2015, Pleiades Publishing, Inc.
引用
收藏
页码:212 / 231
页数:19
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