Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis

被引：0
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作者：
Xin Tracy Liu
Yu Huang
Da Liu
Yingxin Celia Jiang
Min Zhao
Long Hoa Chung
Xingxing Daisy Han
Yinan Zhao
Jinbiao Chen
Paul Coleman
Ka Ka Ting
Collin Tran
Yingying Su
Claude Vincent Dennis
Atul Bhatnagar
Ken Liu
Anthony Simon Don
Mathew Alexander Vadas
Mark Douglas Gorrell
Shubiao Zhang
Michael Murray
Mary Meltem Kavurma
Geoffrey William McCaughan
Jennifer Ruth Gamble
Yanfei Qi
机构：
[1] The University of Sydney,Centenary Institute of Cancer Medicine and Cell Biology
[2] University of the Sunshine Coast,School of Science, Technology and Engineering
[3] Dalian Minzu University,Key Laboratory of Biotechnology and Bioresources Utilization of Ministry of Education
[4] The University of Sydney,School of Medical Sciences, Faculty of Medicine and Health
[5] The University of Sydney,Sydney Microscopy and Microanalysis
[6] Royal Prince Alfred Hospital,AW Morrow Gastroenterology and Liver Centre
[7] Sydney Local Health District,Sydney Mass Spectrometry
[8] The University of Sydney,Sydney Pharmacy School, Faculty of Medicine and Health
[9] The University of Sydney,undefined
[10] Heart Research Institute,undefined
来源：
Journal of Translational Medicine | / 22卷
关键词：
Sphingosine kinase; PF-543; PFKFB3; Angiogenesis; Glycolysis; Hepatocellular carcinoma;
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