Well-Differentiated Liposarcoma/Atypical Lipomatous Tumor of the Oral Cavity: Report of Three Cases and Review of the Literature

被引:13
作者
Piperi E. [1 ]
Tosios K.I. [1 ]
Nikitakis N.G. [1 ]
Kyriakopoulos V.F. [1 ]
Tzerbos F. [2 ]
Koutlas I.G. [3 ]
Sklavounou A. [1 ]
机构
[1] Department of Oral Pathology and Medicine, Dental School, University of Athens, 11527 Athens
[2] Department of Oral and Maxillofacial Surgery, Dental School, University of Athens, Athens
[3] Division of Oral Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN
关键词
Atypical lipoma; Liposarcoma; Oral neoplasms; Soft tissue sarcoma;
D O I
10.1007/s12105-011-0327-2
中图分类号
学科分类号
摘要
Atypical Lipomatous Tumor/Well Differentiated Liposarcoma (ALT/WDLS) is a soft tissue sarcoma of intermediate malignant behavior, most frequently affecting the retroperitoneum and lower extremities. Oral liposarcomas are very rare neoplasms, the most common histological subtype being ALT/WDLS. In this study, three additional cases of ALT/WDLS located on the tongue (2 cases) and the lower lip (1 case), respectively, are described. Analysis of the salient clinicopathologic features of 63 oral ALT/WDLS cases previously reported in the English language literature, as well as of the 3 cases presented in this study, indicates that the indolent biologic behavior of this tumor justifies its designation as a locally spreading malignant neoplasm, affording a rather conservative surgical approach. © 2012 Springer Science+Business Media, LLC.
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页码:354 / 363
页数:9
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