Synthesis of 6-[2-(Benzoxazol-2-ylmethylamino)ethoxy]-1-Alkyl-1H-lndole-2-Carboxylic acid and inhibitory activity on β-Amyloid aggregation

被引：2
|
作者：
Sun Mi Lee
Raok Jeon
机构：
[1] Sookmyung Women’s University,College of Pharmacy
来源：
Archives of Pharmacal Research | 2005年 / 28卷
关键词：
Indole; Alzheimer’s disease; β-Amyloid aggregation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
6-[2-(Benzoxazol-2-ylmethylamino)ethoxy]-1-alkyl-1H-indole-2-carboxylic acids were designed and synthesized as β-amyloid (Aβ) fibril assembly inhibitors. Their inhibitory activity on Aβ, aggregation was evaluated by thioflavin T assay although their activities were insignificant.
引用
收藏
页码：1219 / 1223
页数：4
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