Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer

被引：0
|
作者：
Jichao He
Ronan P. McLaughlin
Vera van der Noord
John A. Foekens
John W. M. Martens
Gerard van Westen
Yinghui Zhang
Bob van de Water
机构：
[1] Leiden University,Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research
[2] Erasmus Medical Centre,Department of Medical Oncology and Cancer Genomic Netherlands, Erasmus MC Cancer Institute
来源：
Breast Cancer Research and Treatment | 2019年 / 178卷
关键词：
Multi-kinase inhibitor; mTOR-targeted therapy; Drug resistance; Triple-negative breast cancer (TNBC); Polypharmacology;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：263 / 274
页数：11
相关论文
共 50 条
  • [31] Targeting chemotherapy resistance in mesenchymal triple-negative breast cancer: a phase II trial of neoadjuvant angiogenic and mTOR inhibition with chemotherapy
    Nour Abuhadra
    Ryan Sun
    Roland L. Bassett
    Lei Huo
    Jeffrey T. Chang
    Mediget Teshome
    Alyson R. Clayborn
    Jason B. White
    Elizabeth E. Ravenberg
    Beatriz E. Adrada
    Rosalind P. Candelaria
    Wei Yang
    Qingqing Ding
    W. Fraser Symmans
    Banu Arun
    Senthil Damodaran
    Kimberly B. Koenig
    Rachel M. Layman
    Bora Lim
    Jennifer K. Litton
    Alastair Thompson
    Naoto T. Ueno
    Helen Piwnica-Worms
    Gabriel N. Hortobagyi
    Vicente Valero
    Debu Tripathy
    Gaiane M. Rauch
    Stacy Moulder
    Clinton Yam
    Investigational New Drugs, 2023, 41 : 391 - 401
  • [32] Targeting chemotherapy resistance in mesenchymal triple-negative breast cancer: a phase II trial of neoadjuvant angiogenic and mTOR inhibition with chemotherapy
    Abuhadra, Nour
    Sun, Ryan
    Bassett, Roland L.
    Huo, Lei
    Chang, Jeffrey T.
    Teshome, Mediget
    Clayborn, Alyson R.
    White, Jason B.
    Ravenberg, Elizabeth E.
    Adrada, Beatriz E.
    Candelaria, Rosalind P.
    Yang, Wei
    Ding, Qingqing
    Symmans, W. Fraser
    Arun, Banu
    Damodaran, Senthil
    Koenig, Kimberly B.
    Layman, Rachel M.
    Lim, Bora
    Litton, Jennifer K.
    Thompson, Alastair
    Ueno, Naoto T.
    Piwnica-Worms, Helen
    Hortobagyi, Gabriel N.
    Valero, Vicente
    Tripathy, Debu
    Rauch, Gaiane M.
    Moulder, Stacy
    Yam, Clinton
    INVESTIGATIONAL NEW DRUGS, 2023, 41 (03) : 391 - 401
  • [33] Investigating the Use of Targeted Therapies for Triple-Negative Breast Cancer
    Bindeman, Wendy
    Redwood, Abena
    Lukose, Benjamin
    Piwnica-Worms, Helen
    FASEB JOURNAL, 2015, 29
  • [34] Moving Towards Targeted Therapies for Triple-Negative Breast Cancer
    Jodi A. Kagihara
    Elena Shagisultanova
    Anosheh Afghahi
    Jennifer R. Diamond
    Current Breast Cancer Reports, 2021, 13 : 216 - 226
  • [35] Recent advances in targeted strategies for triple-negative breast cancer
    Shuangli Zhu
    Yuze Wu
    Bin Song
    Ming Yi
    Yuheng Yan
    Qi Mei
    Kongming Wu
    Journal of Hematology & Oncology, 16
  • [36] A NEW TARGETED THERAPY FOR THE TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER
    Martin, Janet L.
    de Silva, Hasanthi C.
    Scott, Carolyn D.
    Baxter, Robert C.
    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2014, 10 : 13 - 13
  • [37] Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer
    Bai, Longchuan
    Zhou, Bing
    Yang, Chao-Yie
    Ji, Jiao
    McEachern, Donna
    Przybranowski, Sally
    Jiang, Hui
    Hu, Jiantao
    Xu, Fuming
    Zhao, Yujun
    Liu, Liu
    Fernandez-Salas, Ester
    Xu, Jing
    Dou, Yali
    Wen, Bo
    Sun, Duxin
    Meagher, Jennifer
    Stuckey, Jeanne
    Hayes, Daniel F.
    Li, Shunqiang
    Ellis, Matthew J.
    Wang, Shaomeng
    CANCER RESEARCH, 2017, 77 (09) : 2476 - 2487
  • [38] Targeted therapy for triple-negative breast cancer: Where are we?
    Duffy, Michael J.
    McGowan, Patricia M.
    Crown, John
    INTERNATIONAL JOURNAL OF CANCER, 2012, 131 (11) : 2471 - 2477
  • [39] Targeted Liposomal Chemotherapies to Treat Triple-Negative Breast Cancer
    Si, Yingnan
    Zhang, Ya
    Ngo, Hanh Giai
    Guan, Jia-Shiung
    Chen, Kai
    Wang, Qing
    Singh, Ajeet Pal
    Xu, Yuanxin
    Zhou, Lufang
    Yang, Eddy S.
    Liu, Xiaoguang
    CANCERS, 2021, 13 (15)
  • [40] Moving Towards Targeted Therapies for Triple-Negative Breast Cancer
    Kagihara, Jodi A.
    Shagisultanova, Elena
    Afghahi, Anosheh
    Diamond, Jennifer R.
    CURRENT BREAST CANCER REPORTS, 2021, 13 (03) : 216 - 226
12345