Megatrials of Hormonal Replacement Therapy

被引：0
作者：
Barry G. Wren
机构：
[1] Royal Hospital for Women,Sydney Menopause Centre
来源：
Drugs & Aging | 1998年 / 12卷
关键词：
Breast Cancer; Adis International Limited; Endometrial Cancer; Endometrial Hyperplasia; Hormonal Replacement Therapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Despite the fact that estrogen replacement therapy has been demonstrated to be of great value to postmenopausal women, many patients are still reluctant to use it. This is primarily because of fears that sex hormone therapy increases the risk of developing uterine and breast cancer. Because retrospective epidemiological studies have failed to clarify the issue for breast cancer, ambitious prospective trials have been initiated to determine the role of hormones in the development of breast cancer and cardiovascular disease.
引用
收藏
页码：343 / 348
页数：5
相关论文
共 48 条
[1]  
Ettinger B(1985)Long term estrogen replacement therapy prevents bone loss and fractures Ann Intern Med 102 319-24
[2]  
Genant HK(1992)The effect of oestrogen on the female cardiovascular system Med J Aust 157 204-8
[3]  
Cann CE(1988)Post menopausal estrogen use and coronary atherosclerosis Ann Intern Med 108 358-63
[4]  
Wren BG(1985)Non-contraceptive estrogen use and cardiovascular disease Epidemiol Rev 7 80-104
[5]  
Sullivan JM(1996)Effect of oestrogen during menopause on risk and age at onset of Alzheimer’s disease Lancet 348 429-32
[6]  
Zwaag RV(1975)Association of exogenous estrogens and endometrial cancer N Engl J Med 293 1164-8
[7]  
Lemp GF(1976)Estrogens and endometrial cancer in a retirement community N Engl J Med 294 1262-7
[8]  
Bush TL(1979)Endometrial cancer and estrogen use N Engl J Med 300 9-13
[9]  
Barrett-Connor E(1985)Postmenopausal estrogen use, cigarette smoking and cardiovascular morbidity in women over 50: the Framingham Study N Engl J Med 313 1038-43
[10]  
Tang M-X(1985)A prospective study of post menopausal estrogen therapy and coronary heart disease N Engl J Med 313 1044-9
12345