Quality-by-Design Based Development of Doxycycline Hyclate–Loaded Polymeric Microspheres for Prolonged Drug Release

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作者
Suraj Longre
Dhwani Rana
Shagun Rangra
Anil B. Jindal
Sagar Salave
Jyotsna Vitore
Derajram Benival
机构
[1] National Institute of Pharmaceutical Education and Research -Ahmedabad (NIPER-A),Department of Pharmaceutics
[2] Birla Institute of Technology and Science Pilani (BITS PILANI),Department of Pharmacy
来源
AAPS PharmSciTech | / 25卷
关键词
aqueous solubility; burst release; hydrophobic ion pair; lyophilization; microspheres; QbD;
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