Quality-by-Design Based Development of Doxycycline Hyclate–Loaded Polymeric Microspheres for Prolonged Drug Release

被引:0
|
作者
Suraj Longre
Dhwani Rana
Shagun Rangra
Anil B. Jindal
Sagar Salave
Jyotsna Vitore
Derajram Benival
机构
[1] National Institute of Pharmaceutical Education and Research -Ahmedabad (NIPER-A),Department of Pharmaceutics
[2] Birla Institute of Technology and Science Pilani (BITS PILANI),Department of Pharmacy
来源
AAPS PharmSciTech | / 25卷
关键词
aqueous solubility; burst release; hydrophobic ion pair; lyophilization; microspheres; QbD;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 33 条
  • [21] Quality-by-design approach for development and optimization of bupivacaine-loaded nanostructured lipid carrier in situ gel: In vitro, Ex vivo, and In vivo studies for enhanced periodontal anesthesia
    Khan, Sarfaraz
    Khan, Furquan
    ANALYTICAL CHEMISTRY LETTERS, 2025, : 191 - 213
  • [22] Tamoxifen-loaded microspheres based on mixtures of poly(D,L-lactide-co-glycolide) and poly(D,L-lactide) polymers: Effect of polymeric composition on drug release and in vitro antitumoral activity
    Fenandez, A.
    Teijon, C.
    Benito, M.
    Iglesias, I.
    Lozano, R.
    Teijon, J. M.
    Blanco, M. D.
    JOURNAL OF APPLIED POLYMER SCIENCE, 2012, 124 (04) : 2987 - 2998
  • [23] Quality by design enabled formulation development of regorafenib monohydrate loaded PEGylated PLGA polymeric nanoparticles: Enhanced oral bioavailability and biopharmaceutical attributes
    Panigrahi, Dhananjay
    Swain, Suryakanta
    Sahu, Pratap Kumar
    Ghose, Debashish
    Jena, Bikash Ranjan
    NANOMEDICINE JOURNAL, 2024, 11 (04) : 401 - 416
  • [24] Design and In Vitro Evaluation of Eudragit-Based Extended Release Diltiazem Microspheres for Once- and Twice-Daily Administration: The Effect of Coating on Drug Release Behavior
    Bolourchian, Noushin
    Bahjat, Maryam
    TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 16 (03) : 340 - 347
  • [25] Application of a Quality by Design-based approach in development and validation of an RP-HPLC method for simultaneous estimation of methotrexate and mangiferin in dual drug-loaded liposomes
    Adin, Syeda Nashvia
    Gupta, Isha
    Aqil, Mohd.
    Mujeeb, Mohd.
    Najmi, Abul Kalam
    BIOMEDICAL CHROMATOGRAPHY, 2023, 37 (08)
  • [26] Development and in vitro evaluation of pH-independent release matrix tablet of weakly acidic drug valsartan using quality by design tools
    Saydam, Mehtap
    Takka, Sevgi
    DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2018, 44 (12) : 1905 - 1917
  • [27] Fabrication and optimization of extended-release beads of diclofenac sodium based on Ca plus plus cross-linked Taro ( Colocasia esculenta ) stolon polysaccharide and pectin by quality-by-design approach
    Sarkar, Saurav
    Manna, Sreejan
    Das, Esha
    Jana, Piu
    Mukherjee, Saptarshi
    Sahu, Ranabir
    Dua, Tarun Kumar
    Paul, Paramita
    Kaity, Santanu
    Nandi, Gouranga
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 271
  • [28] Development and evaluation of sustained release matrix tablets of pregabalin: A case study based on quality by design to analyze the impact of variables
    Yu, Yonghua
    Xu, Penghe
    Lou, Tingting
    Qin, Benkai
    Zhang, Huina
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 36 (04) : 1191 - 1201
  • [29] Quality by Design (QbD)-Based Numerical and Graphical Optimization Technique for the Development of Osmotic Pump Controlled-Release Metoclopramide HCl Tablets
    Farooqi, Sadaf
    Yousuf, Rabia Ismail
    Shoaib, Muhammad Harris
    Ahmed, Kamran
    Ansar, Sabah
    Husain, Tazeen
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2020, 14 : 5217 - 5234
  • [30] Understanding the Effects of Associated Factors in the Development of Microsponge-Based Drug Delivery: a Statistical Quality by Design (QbD) Approach Towards Optimization
    Shibam Karmakar
    Sourav Poddar
    Jasmina Khanam
    AAPS PharmSciTech, 23