Changes in Apoptosis and Cell Proliferation in Human Pineal Gland during Aging

被引：0

作者：

V. O. Polyakova

N. S. Linkova

S. A. Pichugin

机构：

[1] Saint-Petersburg Institute of Bioregulation and Gerontology,

[2] North-West Division,undefined

[3] Russian Academy of Medical Sciences,undefined

来源：

Bulletin of Experimental Biology and Medicine | 2011年 / 150卷

关键词：

pineal gland; aging; apoptosis; cell proliferation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Immunohistochemical analysis of the expression of proapoptotic protein P53 and proliferation protein Ki-67 in human pineal gland showed that in people over 60 years pinealocyte proliferation is virtually absent. Moreover, pinealocyte apoptosis is more pronounced in elderly, whereas in senile and long-living individuals its intensity decreases.

引用

页码：468 / 470

页数：2