Determination of calibration curves for 131I in thyroid tumour metabolic radiotherapy and other radionuclides used in SPECT imaging

被引：0
作者：
D. Arginelli
J. Heikkonen
A. Miranti
C. Peroni
S. Ridone
L. Vigna
机构：
[1] Agro-Industry and Health Protection,ENEA
[2] Radiation Protection Institute,Italian National Agency for New Technologies, Energy and the Environment, Research Centre of Saluggia, Department of Biotechnologies
[3] Helsinki University Central Hospital,Department of Oncology
[4] University of Turin,Department of Experimental Physics
来源：
Journal of Radioanalytical and Nuclear Chemistry | 2009年 / 282卷
关键词：
Calibration curve; SPECT imaging; Metabolic radiotherapy; Radionuclides; Thyroid tumour; Thyroid dose calculation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
SPECT studies are sensitive but inaccurate means through which to analyze small volumes such as, for instance, remnant tissues after thyroidectomy. We studied the relation between known volumes (0.1–10 cm3) and volumes measured with SPECT studies and using solutions of four different isotopes: 99mTc, 117mSn, 111In, 131I. The curves we determined were tested on SPECT images of two patients treated with 131I. Our work suggests the possibility to evaluate the small remnant mass using calibration curves specific to the system of image acquisition. However, it is necessary to extend the study to a larger number of patients.
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页码：281 / 285
页数：4
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