A fatal case of 3,4-methylenedioxypyrovalerone poisoning: coexistence of α-pyrrolidinobutiophenone and α-pyrrolidinovalerophenone in blood and/or hair

被引：0
作者：
Akira Namera
Shumari Urabe
Takeshi Saito
Aiko Torikoshi-Hatano
Hiroaki Shiraishi
Yousuke Arima
Masataka Nagao
机构：
[1] Hiroshima University,Department of Forensic Medicine, Institute of Biomedical and Health Sciences
[2] Tokai University School of Medicine,Department of Emergency and Critical Care Medicine
来源：
Forensic Toxicology | 2013年 / 31卷
关键词：
3,4-Methylenedioxypyrovalerone (MDPV); α-Pyrrolidinovalerophenone (α-PVP); α-Pyrrolidinobutiophenone (α-PBP); Fatal poisoning; Blood level; Hair analysis;
D O I：
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中图分类号：
学科分类号：
摘要：
We report a fatal case of 3,4-methylenedioxypyrovalerone (MDPV) poisoning. A 35-year-old woman was taken to a nearby hospital after she was found unconscious. MDPV (1,200 ng/ml) and α-pyrrolidinobutiophenone (α-PBP; 200 ng/ml) were detected in her cardiac blood. Hair segments from the victim were also analyzed to confirm chronic drug use. MDPV and α-pyrrolidinovalerophenone (α-PVP) were found in many of the segments tested with the highest MDPV concentration at 22 ng/10-mm hair. We concluded that the woman died of acute MDPV poisoning, and that she had abused MDPV and α-PVP for a long time. To our knowledge, this is the first report dealing with MDPV in human hair segments, and with α-PBP in human specimens.
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页码：338 / 343
页数：5
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