Oxidative Resistance of Na/K-ATPase

被引:0
作者
Ekaterina G. Kurella
Olga V. Tyulina
Alexander A. Boldyrev
机构
[1] Russian Academy of Medical Sciences,Laboratory of Clinical Neurochemistry, Institute of Neurology
[2] International Biotechnological Center of Moscow State University,Department of Biochemistry
来源
Cellular and Molecular Neurobiology | 1999年 / 19卷
关键词
Na/K-ATPase; SH groups; oxidation; hydrogen peroxide; hypochlorite; antioxidants; carnosine;
D O I
暂无
中图分类号
学科分类号
摘要
1. Oxidative modification of Na/K-ATPase from brain and kidney has been studied. Brain enzyme has been found to be more sensitive than kidney enzyme to inhibition by both H2O2 and NaOCl.
引用
收藏
页码:133 / 140
页数:7
相关论文
共 74 条
  • [1] Andreoli S.(1993)Oxidant-induced alterations in glucose and phosphate transport in LLC-PK1 cells: Mechanism of injury Am. J. Physiol. 265 F337-F384
  • [2] McTeer J.(1993)Does carnosine possess direct antioxidant activity? Int. J. Biochem. 25 1101-1107
  • [3] Seifert S.(1995)Effect of hydrogen peroxide and hypochlorite on the activity of brain. Na,K-ATPase Biochemistry 60 1810-1819
  • [4] Kempson S.(1995)Effects of carnosine on generation of free oxygen species: a comparative study Comp. Biochem. Physiol. 112B 481-485
  • [5] Boldyrev A. A.(1997)Biochemical and physiological evidence that carnosine is an endogenous neuroprotector against free radicals Cell. Mol. Neurobiol. 17 259-268
  • [6] Bodyrev A.(1997)Effect of nitroso compounds on Na/K-ATPase Biochem. Biophys. Acta 1321 243-251
  • [7] Bulygina E.(1959)Tissue sulfhydryl groups Arch. Biochem. Biophys. 82 70-77
  • [8] Volynskaya E.(1994)Different sensitivities of the Na:K-ATPase isoforms to oxidants Biochim. Biophys. Acta. 1190 108-114
  • [9] Kurella E.(1988)Depression of membrane-bound Na Am. J. Physiol. 254 C330-C337
  • [10] Tyulina O. V.(1975)-K Anal. Biochem. 67 397-403