Neoadjuvant, inductive or adjuvant chemotherapy of bladder cancer

被引:0
作者
Ohlmann, C. -H. [1 ]
De Santis, M. [2 ]
机构
[1] Univ Klinikum Saarlandes, Klin Urol & Kinderurol, D-66424 Homburg, Germany
[2] Kaiser Franz Josef Spital SMZ Sud, Med Abt 3, Zentrum Onkol & Hamatol & Angew Krebsforsch, Inst Translationale Forsch Wien ACR ITR VIEnna, Vienna, Austria
来源
UROLOGE | 2013年 / 52卷 / 11期
关键词
Cisplatin; Chemotherapy; perioperative; Cystectomy; Lymphadenectomy; Micrometastases; RADICAL CYSTECTOMY; UROTHELIAL CARCINOMA; PHASE-III; PROGNOSTIC VALUE; CISPLATIN; THERAPY; GEMCITABINE; SURVIVAL; TRIAL;
D O I
10.1007/s00120-013-3249-7
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Perioperative chemotherapy is a standard treatment for patients with muscle-invasive bladder carcinoma undergoing radical cystectomy; however, direct comparisons of neoadjuvant and adjuvant chemotherapy are lacking. Evidence-based data and implementation into daily clinical practice favor neoadjuvant chemotherapy; nevertheless, neoadjuvant chemotherapy is still underused in daily practice compared to adjuvant chemotherapy. If neoadjuvant chemotherapy has not been used and patients are fit enough to receive cisplatin, adjuvant chemotherapy should be considered in patients with pT3-pT4 and/or lymph node metastases.
引用
收藏
页码:1534 / +
页数:6
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