Tricellular junctions regulate intestinal stem cell behaviour to maintain homeostasis

被引：0
作者：
Martin Resnik-Docampo
Christopher L. Koehler
Rebecca I. Clark
Joseph M. Schinaman
Vivien Sauer
Daniel M. Wong
Sophia Lewis
Cecilia D’Alterio
David W. Walker
D. Leanne Jones
机构：
[1] Cell,Department of Molecular
[2] and Developmental Biology,Department of Integrative Biology and Physiology
[3] University of California,undefined
[4] University of California,undefined
[5] Molecular Biology Institute,undefined
[6] University of California,undefined
[7] Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research,undefined
[8] University of California,undefined
来源：
Nature Cell Biology | 2017年 / 19卷
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摘要：
Resnik-Docampo et al. demonstrate that depletion of the tricellular junction protein Gliotactin in young flies leads to hallmarks of ageing, including an increase in intestinal stem cell proliferation and a block in terminal differentiation.
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页码：52 / 59
页数：7
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