Induction of apoptosis in HEp-2 cells by infection with herpes simplex virus type 2

被引:0
|
作者
A. H. Koyama
H. Akari
A. Adachi
F. Goshima
Y. Nishiyama
机构
[1] Department of Virology,
[2] School of Medicine,undefined
[3] The University of Tokushima,undefined
[4] Tokushima,undefined
[5] Japan,undefined
[6] Laboratory of Virology,undefined
[7] Research Institute for Disease Mechanism and Control,undefined
[8] Nagoya University School of Medicine,undefined
[9] Nagoya,undefined
[10] Japan,undefined
来源
Archives of Virology | 1998年 / 143卷
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摘要
Although herpes simplex virus type 1 (HSV-1) does not induce apoptosis in infected HEp-2 cells, herpes simplex virus type 2 (HSV-2) did induce apoptosis in a small but significant fraction of the same cells. Apoptosis was not observed in Vero or HeLa cells infected with HSV-2. In addition, HSV-2 infection in the presence of cycloheximide induced extensive apoptosis of HEp-2 or HeLa cells.
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页码:2435 / 2441
页数:6
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