Smooth Muscle Sirtuin 1 Blocks Thoracic Aortic Aneurysm/Dissection Development in Mice

[31] Greiner TC(2003)Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry Circ Res 92 827-839

[32] Zhao Y(2000)Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms J Clin Invest 105 1641-1649

[33] Fiotti N(2011)SIRT1 acts as a modulator of neointima formation following vascular injury in mice Circ Res 108 1180-1189

[34] Baxter BT(2015)The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells Cell Stem Cell 16 171-183

[35] Xiong W(2013)H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction Genome Res 23 2053-2065

[36] Knispel RA(2016)Calorie restriction protects against experimental abdominal aortic aneurysms in mice J Exp Med 213 2473-2488

[37] Dietz HC(2015)Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture Circ Res 116 612-623

[38] Ramirez F(2012)Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection Circulation 126 3070-3080

[39] Baxter BT(2015)Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice Circ Res 117 e13-e26

[40] Chung AW(2009)An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice J Clin Invest 119 3637-3651

[31] Greiner TC(2003)Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry Circ Res 92 827-839

[32] Zhao Y(2000)Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms J Clin Invest 105 1641-1649

[33] Fiotti N(2011)SIRT1 acts as a modulator of neointima formation following vascular injury in mice Circ Res 108 1180-1189

[34] Baxter BT(2015)The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells Cell Stem Cell 16 171-183

[35] Xiong W(2013)H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction Genome Res 23 2053-2065

[36] Knispel RA(2016)Calorie restriction protects against experimental abdominal aortic aneurysms in mice J Exp Med 213 2473-2488

[37] Dietz HC(2015)Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture Circ Res 116 612-623

[38] Ramirez F(2012)Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection Circulation 126 3070-3080

[39] Baxter BT(2015)Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice Circ Res 117 e13-e26

[40] Chung AW(2009)An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice J Clin Invest 119 3637-3651