Omicron: a shift in the biology of SARS-CoV-2

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Nature Microbiology | 2022年 / 7卷
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The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a phenotype that has changed fundamentally compared with preceding variants. Substantial antigenic change within the spike protein and a new endocytic entry mechanism underlie the immune evasion characteristics and a coincident decrease in the virulence of this variant.
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页码:1114 / 1115
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[1]  
Viana R(2022)Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa Nature 603 679-686
[2]  
Meng B(2022)Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity Nature 603 706-714