Urethroplasty with tissue matrix. Microsurgical animal experiments with small intestinal submucosa

被引：1

作者：

Beintkerl, M.

Vogt, B.

Schubert, J.

Schubert, H.

Kosmehl, H.

机构：

[1] Urol Clin, Sudharz Krankenhaus gGmbH, Nordhausen, Germany

[2] Univ Jena, Urol Klin, D-6900 Jena, Germany

[3] Univ Jena, Tierexperimentellesv Zentrum, D-6900 Jena, Germany

[4] HELIOS Klin, Erfurt, Germany

来源：

UROLOGE | 2007年 / 46卷 / 09期

关键词：

urethroplasty; hypospadias; tissue engineering; microsurgery; small intestinal submucosa;

D O I：

10.1007/s00120-007-1495-2

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background. The purpose of this study was to examine whether use of small intestinal submucosa in microsurgical urethroplasty in Wistar rats represents an alternative. Methods. In 20 Wistar rats microsurgical urethroplasty with small intestinal submucosa was done to repair distal or proximal urethral defects. Four weeks later urethral calibration and urethrography were performed in addition to histological studies. Results and conclusions. Of the 20 animals, 19 survived the observation period without evidence of fistulas, strictures, stenoses, or necroses. The histological results confirmed an intact tissue layer.

引用

页码：1236 / 1237

页数：2