Suppression of long non-coding RNA PCAT19 inhibits glioma cell proliferation and invasion, and increases cell apoptosis through regulation of MELK targeted by miR-142-5p

被引:0
作者
Yu-hua Xie
Jiao Hu
机构
[1] Chenzhou No. 1 People’s Hospital,Department of Rehabilitation Medicine
[2] Chenzhou No. 1 People’s Hospital,Emergency Department
来源
Genes & Genomics | 2020年 / 42卷
关键词
LncPCAT19; miR-142-5p; MELK; Xenografts; Glioma;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1299 / 1310
页数:11
相关论文
共 171 条
[1]  
Bartonicek N(2016)Long noncoding RNAs in cancer: mechanisms of action and technological advancements Mol Cancer 15 43-2574
[2]  
Maag JL(2016)Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by suppressing miR-155 expression and activating FBXW7 function Am J Cancer Res 6 2561-4116
[3]  
Dinger ME(2017)Long non-coding RNA XIST promotes glioma tumorigenicity and angiogenesis by acting as a molecular sponge of miR-429 J Cancer 8 4106-1371
[4]  
Cao S(2019)miR-142-5p suppresses proliferation and promotes apoptosis of human osteosarcoma cell line, HOS, by targeting PLA2G16 through the ERK1/2 signaling pathway Oncol Lett 17 1363-1398
[5]  
Wang Y(2014)Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers Mol Cancer Ther 13 1393-2583
[6]  
Li J(2015)MELK-a conserved kinase: functions, signaling, cancer, and controversy Clin Transl Med 4 11-1063
[7]  
Lv M(2018)Risk SNP-mediated promoter-enhancer switching drives prostate cancer through lncRNA PCAT19 Cell 174 e518-112
[8]  
Niu H(2019)LncRNA TTN-AS1 promotes migration, invasion, and epithelial mesenchymal transition of lung adenocarcinoma via sponging miR-142-5p to regulate CDK5 Cell Death Dis 10 573-21949
[9]  
Tian Y(2011)Prevalence estimates for primary brain tumors in China: a multi-center cross-sectional study Chin Med J-Peking 124 2578-1850
[10]  
Cheng Z(2013)MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells Stem Cells 31 1051-v75