Neuropsychological functioning in early-onset first-episode psychosis: comparison of diagnostic subgroups

被引：0
作者：
Arantzazu Zabala
Marta Rapado
Celso Arango
Olalla Robles
Elena de la Serna
Cristina González
José Manuel Rodríguez-Sánchez
Patricia Andrés
María Mayoral
Igor Bombín
机构：
[1] Hospital General Universitario Gregorio Marañón,Adolescent Unit, Department of Psychiatry
[2] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM),Hospital General Universitario Gregorio Marañón
[3] University of the Basque Country (UPV/EHU),Department of Neuroscience
[4] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM),Department of Child and Adolescent Psychiatry and Psychology, Institute Clinic of Neurosciences
[5] IDIBAPS,Stanley Institute International Mood
[6] Hospital Clínic,Disorders Research Center, 03
[7] Universitari of Barcelona,RC
[8] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM),003
[9] Hospital Santiago Apóstol de Vitoria,Child and Adolescent Mental Health Unit, Department of Psychiatry and Psychology
[10] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM),Section of Child and Adolescent Psychiatry and Psychology
[11] Hospital Universitario Marqués de Valdecilla,Neuropsychology Department
[12] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM),Department of Psychiatry
[13] Hospital Infantil Universitario Niño Jesús,undefined
[14] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM),undefined
[15] Reintegra Foundation,undefined
[16] University of Oviedo,undefined
[17] Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM),undefined
来源：
European Archives of Psychiatry and Clinical Neuroscience | 2010年 / 260卷
关键词：
Cognition; Early onset; First episode; Psychosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The aims of this study were to examine the nature and extent of cognitive impairment in first-episode early-onset psychosis (FE-EOP) soon after their stabilisation and to search for potential differences according to specific diagnostic sub-groups of patients. As part of a Spanish multicentre longitudinal study, 107 FE-EOP patients and 98 healthy controls were assessed on the following cognitive domains: attention, working memory, executive functioning, and verbal learning and memory. Three diagnostic categories were established in the patient sample: schizophrenia (n = 36), bipolar disorder (n = 19), and other psychosis (n = 52). Patients performed significantly worse than controls in all cognitive domains. The three diagnostic sub-groups did not differ in terms of impaired/preserved cognitive functions or degree of impairment. FE-EOP patients show significant cognitive impairment that, during this early phase, seems to be non-specific to differential diagnosis.
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页码：225 / 233
页数：8
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