Does zaleplon help you sleep and wake refreshed?

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Zolpidem; Triazolam; Sleep Latency; Zopiclone; Zaleplon;
D O I
10.2165/00042310-199914040-00001
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摘要
Zaleplon is a nonbenzodiazepine hypnotic agent that is effective and well tolerated in the treatment of sleep-initiation insomnia. Initial data suggest that sleep latency, time to return to sleep and sleep efficiency are all improved with zaleplon. Bedtime doses of the drug have not caused significant next-day psychomotor or memory impairment in studies to date, and discontinuation of zaleplon has not resulted in significant rebound insomnia.
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  • [1] Walsh J.K., Zaleplon, CNS Drugs, 11, 5, (1999)
  • [2] Wagner J., Wagner M.L., Hening W.A., Beyond benzodiazepines: Alternative pharmacologic agents for the treatment of insomnia, Ann Pharmacother, 32, pp. 680-691, (1998)
  • [3] Beer B., Clody D.E., Mangano R., Et al., A review of the preclinical development of zaleplon, a novel non-benzodiazepine hypnotic for the treatment of insomnia, CNS Drug Rev, 3, 3, pp. 207-224, (1997)
  • [4] Hurst M., Noble S., Zaleplon, CNS Drugs, 11, 5, pp. 387-392, (1999)
  • [5] Langtry H.D., Benfield P., Zolpidem. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential, Drugs, 40, 2, pp. 291-313, (1990)
  • [6] Sanger D.J., Depoortere H., The pharmacology and mechanism of action of zolpidem, CNS Drug Rev, 4, 4, pp. 323-340, (1998)
  • [7] Physicians' Desk Reference. 52nd Ed., pp. 2275-2278, (1998)
  • [8] British National Formulary. No. 37, 37, pp. 159-162, (1999)
  • [9] Noble S., Langtry H.D., Lamb H.M., Zopiclone. An update of its pharmacology, clinical efficacy and tolerability in the treatment of insomnia, Drugs, 55, 2, pp. 277-302, (1998)
  • [10] Walsh J.K., Fry J., Erwin C.W., Et al., Efficacy and tolerability of 14-day administration of zaleplon 5mg and 10mg for the treatment of primary insomnia, Clin Drug Invest, 16, 5, pp. 347-354, (1998)