Glaucocalyxin A suppresses multiple myeloma progression in vitro and in vivo through inhibiting the activation of STAT3 signaling pathway

被引:0
作者
Mei Li
Cailong Chen
Qian Wang
Xiaolu Jiang
Lanlan Tan
Ying Huang
Yan Zhang
Zubin Zhang
机构
[1] Children’s Hospital of Soochow University,Institute of Pediatric Research
[2] Children’s Hospital of Soochow University,Children Health Management Center
[3] Children’s Hospital of Soochow University,Department of Anesthesiology
[4] The First Affiliated Hospital of Soochow University,Department of Ultrasound
[5] The Affiliated Hospital of Nanjing Medical University,Department of Gynecology and Obstetrics, Wuxi Maternal and Child Health Hospital
[6] Soochow University,Jiangsu Key Laboratory of Neuropsychiatric Diseases, Department of Pharmacology, College of Pharmaceutical Sciences
来源
Cancer Cell International | / 21卷
关键词
STAT3; Apoptosis; Cell cycle; Glaucocalyxin A; Multiple myeloma;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 237 条
[1]  
Eslick R(2013)Multiple myeloma: from diagnosis to treatment Aust Fam Physician 42 684-688
[2]  
Talaulikar D(2011)Multiple myeloma N Engl J Med 364 1046-1060
[3]  
Palumbo A(2020)The safety of current and emerging therapies for multiple myeloma Expert Opin Drug Saf 19 269-279
[4]  
Anderson K(2003)Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat 3 activation and cyclin D1 dysregulation are mutually exclusive events Am J Pathol 162 1449-1461
[5]  
Nadeem O(2019)STAT3: a promising therapeutic target in multiple myeloma Cancers 9 798-809
[6]  
Anderson KC(2009)STATs in cancer inflammation and immunity: a leading role for STAT3 Nat Rev Cancer 59 2068-2074
[7]  
Quintanilla-Martinez L(2021)The multifaced role of STAT3 in cancer and its implication for anticancer therapy Int J Mol Sci 15 234-248
[8]  
Kremer M(2018)STAT3 inhibition as a therapeutic strategy for leukemia Leuk Lymphoma 8 708-3604
[9]  
Specht K(2018)Targeting the IL-6/JAK/STAT3 signalling axis in cancer Nat Rev Clin Oncol 9 3595-1290
[10]  
Calzada-Wack J(2013)Glaucocalyxin A inhibits platelet activation and thrombus formation preferentially via GPVI signaling pathway PLoS ONE 22 1280-5810