A Study of Haloperidol Inclusion Complexes with β-Cyclodextrin Using Phase Solubility, NMR Spectroscopy and Molecular Modeling Techniques

被引：0

作者：

Mahmoud M. Al Omari

Mohammad B. Zughul

J. Eric D. Davies

Adnan A. Badwan

机构：

[1] The Jordanian Pharmaceutical Manufacturing Company,Department of Chemistry

[2] University of Jordan,Department of Environmental Science

[3] Lancaster University,undefined

来源：

Journal of Solution Chemistry | 2009年 / 38卷

关键词：

Haloperidol; Aqueous p; Cyclodextrin; Hydrophobic effect; H-NMR; Molecular modeling;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Guest-host interactions of haloperidol (Halo) with β-cyclodextrin (β-CD) have been investigated using several techniques including phase solubility diagrams (PSD), proton nuclear magnetic resonance (1H-NMR), X-ray powder diffractometry (XRPD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and molecular mechanical modeling (MM+).

引用

页码：669 / 683

页数：14

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