A Study of Haloperidol Inclusion Complexes with β-Cyclodextrin Using Phase Solubility, NMR Spectroscopy and Molecular Modeling Techniques

被引：0
|
作者：
Mahmoud M. Al Omari
Mohammad B. Zughul
J. Eric D. Davies
Adnan A. Badwan
机构：
[1] The Jordanian Pharmaceutical Manufacturing Company,Department of Chemistry
[2] University of Jordan,Department of Environmental Science
[3] Lancaster University,undefined
来源：
Journal of Solution Chemistry | 2009年 / 38卷
关键词：
Haloperidol; Aqueous p; Cyclodextrin; Hydrophobic effect; H-NMR; Molecular modeling;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Guest-host interactions of haloperidol (Halo) with β-cyclodextrin (β-CD) have been investigated using several techniques including phase solubility diagrams (PSD), proton nuclear magnetic resonance (1H-NMR), X-ray powder diffractometry (XRPD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and molecular mechanical modeling (MM+).
引用
收藏
页码：669 / 683
页数：14
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