Genetic aspects in attention-deficit/hyperactivity disorder

被引:0
作者
Ö. Albayrak
S. Friedel
B. G. Schimmelmann
A. Hinney
J. Hebebrand
机构
[1] University of Duisburg-Essen,Department of Child and Adolescent Psychiatry, Rheinische Kliniken Essen
来源
Journal of Neural Transmission | 2008年 / 115卷
关键词
Keywords: ADHD; dopamine; genetics; risk factor;
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学科分类号
摘要
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this complex disease. Genetic research comprises formal genetic studies, candidate gene studies, linkage analyses, and recently large-scale genome wide association studies, gene-environement interaction studies, and pharmacogenetics. This article comprehensively reviews the latest findings on the genetics of ADHD.
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页码:305 / 315
页数:10
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