Influence of Molecular Characteristics of Chitosan on Properties of In situ Formed Scaffolds

被引：7
|
作者：
Grigoriev T.E. [1 ]
Zagoskin Y.D. [1 ]
Belousov S.I. [1 ]
Vasilyev A.V. [2 ,3 ]
Bukharova T.B. [3 ]
Leonov G.E. [2 ,3 ]
Galitsyna E.V. [3 ]
Goldshtein D.V. [2 ,3 ]
Chvalun S.N. [1 ]
Kulakov A.A. [2 ]
Paltsev M.A. [4 ]
机构：
[1] NRC “Kurchatov Institute”, bld. 1, Akademika Kurchatova pl, Moscow
[2] Central Research Institute of Dental and Maxillofacial Surgery, bld. 16, Timura Frunze st, Moscow
[3] Research Centre for Medical Genetics, bld. 1, Moskvorechie st, Moscow
[4] N. M. Emanuel Institute of Biochemical Physics, bld. 4, Kosygin st, Moscow
来源：
BioNanoScience | 2017年 / 7卷 / 3期
关键词：
Chitosan; Deacetylation degree; Gelation kinetics; Hydrogel; Molecular weight; Osteoplastic material; Rheology;
D O I：
10.1007/s12668-017-0411-5
中图分类号：
学科分类号：
摘要：
Effects of molecular weight and degree of deacetylation of chitosan on the properties of chitosan/beta-glycerophosphate situ forming gel were investigated. Storage modulus grows with a decrease of the degree of deacetylation of the chitosan whereas molecular weight has not so strong influence on storage modulus. Higher molecular weight chitosans showed lower cytotoxicity. © 2017, Springer Science+Business Media New York.
引用
收藏
页码：492 / 495
页数：3
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