The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

被引：0
|
作者：
Christopher J Chan
Ludovic Martinet
Susan Gilfillan
Fernando Souza-Fonseca-Guimaraes
Melvyn T Chow
Liam Town
David S Ritchie
Marco Colonna
Daniel M Andrews
Mark J Smyth
机构：
[1] Cellular Immunity Laboratory,Department of Immunology
[2] Cancer Immunology Program,Department of Pathology and Immunology
[3] Trescowthick Research Laboratories,Sir Peter MacCallum Department of Oncology
[4] Peter MacCallum Cancer Centre,undefined
[5] Monash University,undefined
[6] Alfred Medical Research and Education Precinct,undefined
[7] Immunology in Cancer and Infection Laboratory,undefined
[8] QIMR Berghofer Medical Research Institute,undefined
[9] Washington University School of Medicine,undefined
[10] Hematology Immunology Translational Research Laboratory,undefined
[11] Peter MacCallum Cancer Centre,undefined
[12] University of Melbourne,undefined
[13] School of Medicine,undefined
[14] University of Queensland,undefined
来源：
Nature Immunology | 2014年 / 15卷
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中图分类号：
学科分类号：
摘要：
The function of the lymphocyte-expressed receptor CD96 is almost entirely unknown. Smyth and colleagues demonstrate that it serves a key role in restraining activation of NK cells in part by competing with the activating receptor CD226 (DNAM-1).
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页码：431 / 438
页数：7
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