Role and therapeutic potential of Glycodelin A in systemic lupus erythematosus

被引：0
|
作者：
Hai-Feng Pan
Rui-Xue Leng
Ning Zhang
Jin-Hui Tao
Dong-Qing Ye
机构：
[1] Anhui Medical University,Department of Epidemiology and Biostatistics, School of Public Health
[2] Anhui Provincial Hospital,Department of Rheumatology
来源：
Rheumatology International | 2011年 / 31卷
关键词：
Glycodelin A; Systemic lupus erythematosus; Therapeutic target;
D O I：
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学科分类号：
摘要：
Glycodelin A (GdA) is a lipocalin with an immunomodulatory role. Low expression of GdA has been implicated in the progression of autoimmune disease. Therefore, strategies targeting GdA may constitute an important target for the design of drugs for autoimmune disease including systemic lupus erythematosus (SLE). This opinion article will focus on current understanding of the role of GdA in the physiological and pathological functions associated with SLE. It is the intention of the article to provide insights that may assist in the development of GdA-based approaches for the treatment of SLE.
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页码：563 / 565
页数：2
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