Recovery of paraneoplastic hypercalcemia by sunitinib treatment for renal cell carcinoma: a case report and review of the literature

被引：0
作者：
Halit Karaca
Ayhan Lale
Mustafa Dikilitas
Metin Ozkan
Ozlem Er
机构：
[1] Erciyes University Medical Faculty,Departments of Internal Medicine
[2] Erciyes University Medical Faculty,Departments of Medical Oncology
来源：
Medical Oncology | 2010年 / 27卷
关键词：
Renal cell carcinoma; Paraneoplastic hypercalcemia; Sunitinib;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Sunitinib is a novel oral multitargeted tyrosine kinase inhibitor. İt has higher response rates and progression-free survival in patients with metastatic renal cell carcinoma (RCC) when compared with standard chemotherapy and interferon-α. We report a case of paraneoplastic hypercalcemia, resistant to conventional treatment but recovers by sunitinib treatment as the first case in the literature, in a 33-years-old man with metastatic RCC. At the sixth month of follow-up period, in this case, serum calcium level was still in normal ranges. Besides sunitinib is effective in symptom control, it is also helpful in management of paraneoplastic hypercalcemia, a life-threatening entity.
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页码：1023 / 1026
页数：3
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