Lipotoxicity-induced circGlis3 impairs beta cell function and is transmitted by exosomes to promote islet endothelial cell dysfunction

[1] Zheng Y(2018)Global aetiology and epidemiology of type 2 diabetes mellitus and its complications Nat Rev Endocrinol 14 88-98

[2] Ley SH(2013)The origins and drivers of insulin resistance Cell 152 673-684

[3] Hu FB(2016)The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux J Clin Invest 126 12-22

[4] Johnson AM(2018)Effects of dietary fatty acids in pancreatic beta cell metabolism, implications in homeostasis Nutrients 10 393-303

[5] Olefsky JM(2017)Markers of islet endothelial dysfunction occur in male B6.BKS(D)-Leprdb/J mice and may contribute to reduced insulin release Endocrinology 158 293-128

[6] Samuel VT(2017)Intra-islet endothelial cell and beta-cell crosstalk: implication for islet cell transplantation World J Transplant 7 117-1954

[7] Shulman GI(2011)Thrombospondin-1: an islet endothelial cell signal of importance for beta-cell function Diabetes 60 1946-3847

[8] Acosta-Montano P(2020)Circular RNA-ZNF532 regulates diabetes-induced retinal pericyte degeneration and vascular dysfunction J Clin Invest 130 3833-83

[9] Garcia-Gonzalez V(2018)Circular RNAs as novel regulators of beta-cell functions in normal and disease conditions Mol Metab 9 69-691

[10] Hogan MF(2019)The biogenesis, biology and characterization of circular RNAs Nat Rev Genet 20 675-3928

[1] Zheng Y(2018)Global aetiology and epidemiology of type 2 diabetes mellitus and its complications Nat Rev Endocrinol 14 88-98

[2] Ley SH(2013)The origins and drivers of insulin resistance Cell 152 673-684

[3] Hu FB(2016)The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux J Clin Invest 126 12-22

[4] Johnson AM(2018)Effects of dietary fatty acids in pancreatic beta cell metabolism, implications in homeostasis Nutrients 10 393-303

[5] Olefsky JM(2017)Markers of islet endothelial dysfunction occur in male B6.BKS(D)-Leprdb/J mice and may contribute to reduced insulin release Endocrinology 158 293-128

[6] Samuel VT(2017)Intra-islet endothelial cell and beta-cell crosstalk: implication for islet cell transplantation World J Transplant 7 117-1954

[7] Shulman GI(2011)Thrombospondin-1: an islet endothelial cell signal of importance for beta-cell function Diabetes 60 1946-3847

[8] Acosta-Montano P(2020)Circular RNA-ZNF532 regulates diabetes-induced retinal pericyte degeneration and vascular dysfunction J Clin Invest 130 3833-83

[9] Garcia-Gonzalez V(2018)Circular RNAs as novel regulators of beta-cell functions in normal and disease conditions Mol Metab 9 69-691

[10] Hogan MF(2019)The biogenesis, biology and characterization of circular RNAs Nat Rev Genet 20 675-3928