Thermal study on complexes with Schiff base derived from 1,2,4-triazole as potential antimicrobial agents

被引：0
作者：
Larisa Calu
Mihaela Badea
Denisa Falcescu
Daria Duca
Dana Marinescu
Rodica Olar
机构：
[1] University of Bucharest,Department of Inorganic Chemistry, Faculty of Chemistry
来源：
Journal of Thermal Analysis and Calorimetry | 2013年 / 111卷
关键词：
Acetylacetone; Complex; Schiff base; 1,2,4-Triazole; Thermal behaviour;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In order to develop new metallo-antimicrobials the complexes of type MLCl·nH2O ((1) M: Co, n = 0; (2) M: Ni, n = 2; (3) M: Cu, n = 2.5; (4) M: Zn, n = 0, HL: Schiff base derived from acetylacetone and 3-amino-4H-1,2,4-triazole) were synthesized by template condensation. The features of complexes have been assigned from microanalytical, IR and UV–Vis-NIR data. The species heating in air evidenced processes as melting, water and hydrochloride endothermic elimination as well as oxidative degradation of the Schiff base. The temperature ranges as well as modification in the electronic spectra of dehydrated intermediates indicate the presence of both coordination and crystallisation water molecules. The final product of decomposition was the most stable metal oxide as powder X-ray diffraction indicated.
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页码：1725 / 1730
页数：5
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[1]  
Shujah S(2011)New dimeric and supramolecular organotin(IV) complexes with a tridentate Schiff base as potential biocidal agents J Organomet Chem 696 2772-2781
[2]  
Rehman Z-u(2011)Synthesis, structural, thermal studies and biological activity of a tridentate Schiff base ligand and their transition metal complexes Spectrochimica Acta Part A 78 36-44
[3]  
Muhammad N(2011)Synthesis, characterization, in vitro antimicrobial and DNA cleavage studies of Co(II), Ni(II) and Cu(II) complexes with ONOO donor coumarin Schiff bases J Mol Struct 985 330-338
[4]  
Ali S(2011)Metallation of ethylenediamine based Schiff base with biologically active Cu(II), Ni(II) and Zn(II) ions: synthesis, spectroscopic characterization, electrochemical behaviour, DNA binding, photonuclease activity and in vitro antimicrobial efficacy Spectrochim Acta Part A 79 873-883
[5]  
Khalid N(2011)DNA interaction, antimicrobial, electrochemical and spectroscopic studies of metal(II) complexes with tridentate heterocyclic Schiff base derived from 20-methylacetoacetanilide J Mol Struct 1000 135-144
[6]  
Tahir MN(2011)Synthesis, spectral characterization, solution equilibria, in vitro antibacterial and cytotoxic activities of Cu(II), Ni(II), Mn(II), Co(II) and Zn(II) complexes with Schiff base derived from 5-bromosalicylaldehyde and 2-aminomethylthiophene Spectrochim Acta Part A 79 1803-1814
[7]  
El-halima HFA(2009)Design, synthesis and molecular modeling study of acylated 1,2,4-triazole-3-acetates with potential anti-inflammatory activity Eur J Med Chem 44 117-123
[8]  
Omar MM(2011)Arylazolylthioacetanilide. Part 8q: design, synthesis and biological evaluation of novel 2-(2-(2,4-Dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)- Eur J Med Chem 46 539-545
[9]  
Mohamed GG(2011)-arylacetamides as potent HIV-1 inhibitors Dalton Trans 40 6532-6540
[10]  
Patil SA(2011)Mononuclear copper(II) complexes with 3,5-substituted-4-salicylidene-amino-3,5-dimethyl-1,2,4-triazole: synthesis, structure and potent inhibition of protein tyrosine phosphatases Asian J Chem 23 4067-4071
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