miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

被引：0
|
作者：
Li-Chun Cheng
Erika Pastrana
Masoud Tavazoie
Fiona Doetsch
机构：
[1] College of Physicians and Surgeons,Departments of Pathology and Cell Biology Columbia University
[2] Columbia University,Department of Neuroscience
[3] College of Physicians and Surgeons,Department of Neurology
[4] Columbia University,undefined
[5] College of Physicians and Surgeons,undefined
[6] Center for Motor Neuron Biology and Disease,undefined
[7] Columbia University,undefined
[8] College of Physicians and Surgeons,undefined
来源：
Nature Neuroscience | 2009年 / 12卷
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D O I：
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学科分类号：
摘要：
This study shows that the microRNA miR-124 is required for neuronal differentiation of adult neural progenitors in vitro and in vivo. The transcription factor Sox9 opposes neuronal differentiation and is suppressed by miRNA-124.
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页码：399 / 408
页数：9
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