miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

被引：0

作者：

Li-Chun Cheng

Erika Pastrana

Masoud Tavazoie

Fiona Doetsch

机构：

[1] College of Physicians and Surgeons,Departments of Pathology and Cell Biology Columbia University

[2] Columbia University,Department of Neuroscience

[3] College of Physicians and Surgeons,Department of Neurology

[4] Columbia University,undefined

[5] College of Physicians and Surgeons,undefined

[6] Center for Motor Neuron Biology and Disease,undefined

[7] Columbia University,undefined

[8] College of Physicians and Surgeons,undefined

来源：

Nature Neuroscience | 2009年 / 12卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

This study shows that the microRNA miR-124 is required for neuronal differentiation of adult neural progenitors in vitro and in vivo. The transcription factor Sox9 opposes neuronal differentiation and is suppressed by miRNA-124.

引用

页码：399 / 408

页数：9

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