A male patient with metachronous triple cancers of small cell lung, prostate and breast

被引：7

作者：

Baba M. ^{[1
]}

Higaki N. ^{[1
]}

Ishida M. ^{[1
]}

Kawasaki H. ^{[1
]}

Kasugai T. ^{[2
]}

Wada A. ^{[2
]}

机构：

[1] Department of Surgery, Kashiwara Municipal Hospital, Kashiwara 582-0005

[2] Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases

来源：

Breast Cancer | 2002年 / 9卷 / 2期

关键词：

Male breast cancer; Prostatic cancer; Small cell lung cancer;

D O I：

10.1007/BF02967583

中图分类号：

学科分类号：

摘要：

We present a very rare case of metachronous triple cancers, including small cell carcinoma of the lung, as well as prostate and male breast cancer. To our knowledge, this is the first documented case of its kind. A 64-year-old man was referred to our hospital with left nipple retraction. He had previously undergone lobectomy of the fight lung as treatment for small cell lung cancer at 57 years of age, and at 61 years of age, he had undergone prostatectomy and bilateral orchiectomy for prostate cancer, histologically determined to be moderately or poorly differentiated adenocarcinoma. Physical examination identified a painless irregular hard tumor in the left breast. Ultrasonography and magnetic resonance imaging (MRI) showed a nodular mass, and fine needle aspiration cytology of the mass revealed adenocarcinoma. Modified radical mastectomy was performed. Histological examination revealed that the breast tumor was scirrhous carcinoma, tl, no, mo, stage I. Immunohistochemistry demonstrated that the prostate tumor was positive for prostatic specific antigen (PSA) and negative for estrogen receptor (ER), while the breast tumor was positive for ER and negative for PS/k Primary breast cancer was diagnosed. At present, 1 year and 8 months after surgical removal of the breast cancer, the patient has had no recurrence of breast cancer, small cell lung cancer, or prostate cancer. We discuss the possible causes of the triple cancers in this case with reference to the literature.

引用

页码：170 / 174

页数：4

共 37 条

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