Topiramate-induced psychosis in two members of the one family: A case report

被引：6

作者：

José R.J.P. ^{[1
]}

Cairns A. ^{[1
]}

Babbs C. ^{[1
]}

机构：

[1] Department of Medicine, Salford Royal NHS Foundation Trust, Salford M6 8HD, Stott Lane

来源：

Journal of Medical Case Reports | / 2卷 / 1期

关键词：

Topiramate; Bulimia Nervosa; Essential Tremor; Labetalol; Visual Hallucination;

D O I：

10.1186/1752-1947-2-195

中图分类号：

学科分类号：

摘要：

Introduction: The use of topiramate has increased in recent years. It is now used by various specialties to treat a wide range of medical conditions. A small number of case reports describe psychosis as an adverse event of topiramate but most are in patients being treated for epilepsy and none describe a family history of this side effect. Case presentation: We present a case report of topiramate-induced psychosis in a patient with familial essential tremor, whose sister also developed this same adverse effect. Conclusion: Physicians need to be aware of psychosis as a rare but debilitating side effect of this drug. Several predictors have been identified and a careful history, including family history, needs to be obtained prior to initiation of therapy to stratify the risk. © 2008 José et al; licensee BioMed Central Ltd.

引用

共 6 条

[1]

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[2]

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[3]

Zesiewicz T.A., Tullidge A., Tidwell J., Sullivan K.L., Hauser R.A., Topiramate-induced psychosis in patients with essential tremor: Report of 2 cases, Clin Neuropharmacol, 29, pp. 168-169, (2006)

[4]

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[5]

Mula M., Trimble M.R., Lhatoo S.D., Sander J.W., Topiramate and psychiatric adverse events in patients with epilepsy, Epilepsia, 44, pp. 659-663, (2003)

[6]

Kanner A.M., Wuu J., Faught E., Tatum IV W.O., Fix A., French J.A., A past psychiatric history may be a risk factor for topiramate-related psychiatric and cognitive adverse events, Epilepsy Behav, 4, pp. 548-552, (2003)

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