Multiple doses of hepatitis B recombinant vaccine for chronic hepatitis B patients with low surface antigen levels: a pilot study

被引:0
作者
Ming-Wei Lai
Chao-Wei Hsu
Chih-Lang Lin
Rong-Nan Chien
Wey-Ran Lin
Chi-Sheng Chang
Kung-Hao Liang
Chau-Ting Yeh
机构
[1] Chang Gung Memorial Hospital,Division of Pediatric Gastroenterology, Department of Pediatrics
[2] Chang Gung Memorial Hospital,Liver Research Center
[3] Chang Gung University,Molecular Medicine Research Center, College of Medicine
[4] Keelung Chang Gung Memorial Hospital,Liver Research Unit
[5] Taipei Veterans General Hospital,Medical Research Department
来源
Hepatology International | 2018年 / 12卷
关键词
Hepatitis B virus; Surface antigen clearance; Therapeutic vaccine; Human leukocyte antigen; Vaccine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:456 / 464
页数:8
相关论文
共 156 条
  • [1] Lucifora J(2014)Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA Science 343 1221-1228
  • [2] Xia Y(2017)HBeAg seroconversion in HBeAg-positive chronic hepatitis B patients receiving long-term nucleos(t)ide analog treatment: a systematic review and network meta-analysis PLoS One 12 e0169444-1468
  • [3] Reisinger F(2007)Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response Clin Gastroenterol Hepatol 5 1462-1944
  • [4] Zhang K(2010)Serum hepatitis B surface antigen and hepatitis B e antigen titers: disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers Hepatology 51 1933-1168
  • [5] Stadler D(2010)Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion PLoS Pathog 6 e1000986-4225
  • [6] Cheng X(2010)The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein J Immunol 185 1158-1503
  • [7] Xing T(2007)Characterization of hepatitis b virus (HBV)-specific T-cell dysfunction in chronic HBV infection J Virol 81 4215-778
  • [8] Xu H(2011)Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection Hepatology 53 1494-766
  • [9] Cao L(2005)Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection Hepatology 41 771-460
  • [10] Ye M(2010)Antigen-presenting cell function in the tolerogenic liver environment Nat Rev Immunol 10 753-787