Quantitative phosphoproteomic analysis reveals reciprocal activation of receptor tyrosine kinases between cancer epithelial cells and stromal fibroblasts

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作者
Xinyan Wu
Muhammad Saddiq Zahari
Santosh Renuse
Nandini A. Sahasrabuddhe
Raghothama Chaerkady
Min-Sik Kim
Mary Jo Fackler
Martha Stampfer
Edward Gabrielson
Saraswati Sukumar
Akhilesh Pandey
机构
[1] Johns Hopkins University,Department of Biological Chemistry
[2] Johns Hopkins University,McKusick
[3] Institute of Bioinformatics,Nathans Institute of Genetic Medicine
[4] International Technology Park,Department of Oncology
[5] Manipal Academy of Higher Education,Department of Pathology
[6] Johns Hopkins University School of Medicine,Division of Biological Systems and Engineering
[7] Johns Hopkins University School of Medicine,undefined
[8] Lawrence Berkeley National Laboratory,undefined
[9] Johns Hopkins University,undefined
来源
Clinical Proteomics | 2018年 / 15卷
关键词
Breast cancer; Epithelial cell; Carcinoma-associated fibroblast; Signaling crosstalk; SILAC; Phosphoproteome; Mass spectrometry; Co-culture;
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