Gastrointestinal Surgery for Obesity and Diabetes: Weight Loss and Control of Hyperglycemia

被引：0
作者：
H. M. Heneghan
S. Nissen
P. R. Schauer
机构：
[1] Cleveland Clinic,Bariatric and Metabolic Institute, M61
[2] Cleveland Clinic,Heart & Vascular Institute
来源：
Current Atherosclerosis Reports | 2012年 / 14卷
关键词：
Obesity; Diabetes mellitus; Bariatric surgery; Metabolic surgery; Diabetes remission; Weight loss;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Obesity is associated with a variety of weight-related metabolic comorbidities. Bariatric surgery (metabolic/gastrointestinal surgery) not only achieves significant and sustainable weight loss, but also induces extraordinary effects on nearly all obesity-related comorbidities, particularly remission of type 2 diabetes mellitus (T2DM). The mechanisms underlying such effects are slowly being elucidated, and it appears that the metabolic benefits of bariatric surgery are not only attributable to weight loss, but there are also weight independent mechanisms at play. This article outlines the metabolic effects of the most commonly performed bariatric procedures, with a particular emphasis on how they affect glucose metabolism and T2DM.
引用
收藏
页码：579 / 587
页数：8
相关论文
共 232 条
[1]  
Adams KF(2006)Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old N Engl J Med 355 763-778
[2]  
Schatzkin A(2012)Maintained intentional weight loss reduces cardiovascular outcomes: results from the Sibutramine Cardiovascular OUTcomes (SCOUT) trial Diabetes Obes Metab 14 523-530
[3]  
Harris TB(2012)Bariatric surgery and long-term cardiovascular events JAMA 307 56-65
[4]  
Caterson ID(2002)Medical and surgical options in the treatment of severe obesity Am J Surg 184 9S-16S
[5]  
Finer N(2010)Prevalence and trends in obesity among US adults, 1999–2008 JAMA 303 235-241
[6]  
Coutinho W(2006)Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999–2002: the National Health and Nutrition Examination Survey Diabetes Care 29 531-537
[7]  
Sjostrom L(2004)Bariatric surgery: a systematic review and meta-analysis JAMA 292 1724-1737
[8]  
Peltonen M(2011)International Diabetes Federation position statement on bariatric surgery for type 2 diabetes: implications for patients, physicians, and surgeons Surg Obes Relat Dis 7 448-451
[9]  
Jacobson P(2007)Effects of bariatric surgery on mortality in Swedish obese subjects N Engl J Med 357 741-752
[10]  
Fisher BL(2007)Long-term mortality after gastric bypass surgery N Engl J Med 357 753-761
12345678910