UV-initiated crosslinking of electrospun chitosan/poly(ethylene oxide) nanofibers doped with ZnO-nanoparticles: development of antibacterial nanofibrous hydrogel

被引:0
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作者
G. M. Estrada-Villegas
J. I. Del Río-De Vicente
L. Argueta-Figueroa
G. González-Pérez
机构
[1] Av. Alianza Sur 204 Parque de Innovación e Investigación Tecnológica,CONACyT — Centro de Investigación en Química Aplicada
[2] Universidad Autónoma Benito Juárez de Oaxaca,CONACyT — Facultad de Odontología
[3] Instituto Tecnológico de Nuevo León,Departamento de Ingeniería, Tecnológico Nacional de México
[4] Av. Eloy Cavazos,undefined
来源
MRS Communications | 2020年 / 10卷
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摘要
UV-initiated crosslinking of electrospun poly(ethylene) oxide (PEO)/chitosan (CS) nanofibers doped with zinc oxide nanoparticles (ZnO-NPs) was performed using pentaerythritol triaclyrate (PETA) as the photoinitiator and crosslinker agent. The influence of the addition of PETA to the PEO/CS diameter and crosslinking of nanofibers was evaluated. The effect of irradiation time on the morphology and swelling properties of the crosslinked nanofibers were investigated. For ZnO-NPs, the minimum inhibitory concentrations were found at 1 mg/mL, and the minimum bactericidal concentrations at 2 mg/mL for all the strains tested. The nanofibrous hydrogel antibacterial effect was tested. This material enters the realm of fibrous hydrogels which have potential use in several applications as in the biomedical area.
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页码:642 / 651
页数:9
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