Targeting Drosophila eye development

被引:0
作者
Jennifer Jemc
Ilaria Rebay
机构
[1] Massachusetts Institute of Technology,Department of Biology
[2] University of Chicago,Ben May Institute for Cancer Research
来源
Genome Biology | / 7卷
关键词
Direct Transcriptional Target; Morphogenetic Furrow; Epistasis Analysis; Retinal Determination; Linear Signaling Pathway;
D O I
暂无
中图分类号
学科分类号
摘要
In order to understand the role of transcription factors in particular developmental processes it is necessary to know their target genes. A combination of bioinformatics, comparative expression profiling and microarray-based epistasis experiments has recently identified new targets of Eyeless, a key transcription factor in Drosophila retinal determination.
引用
收藏
相关论文
共 80 条
[1]  
Ostrin EJ(2006)Genome-wide identification of direct targets of the Genome Res 16 466-476
[2]  
Li Y(2003)retinal determination protein Eyeless. Proc Natl Acad Sci USA 100 4024-4029
[3]  
Hoffman K(2005)Analysis of the eye developmental pathway in Development 132 3-13
[4]  
Liu J(1996)using DNA microarrays. Development 122 4139-4147
[5]  
Wang K(2002)Signaling circuitries in development: insights from the retinal determination gene network. Proc Natl Acad Sci USA 99 757-762
[6]  
Zhang L(2002)Atonal, rough and the resolution of proneural clusters in the developing Development 129 625-634
[7]  
Mardon G(2005)retina. Dev Cell 8 255-266
[8]  
Chen R(2005)Exploiting transcription factor binding site clustering to identify Dev Cell 8 241-253
[9]  
Michaut L(1998)-regulatory modules involved in pattern formation in the Development 125 2181-2191
[10]  
Flister S(1997)genome. Cell 91 881-891