Nanotechnology and COVID-19: quo vadis?

被引:0
作者
João Lima Tavares
Iago Dillion Lima Cavalcanti
Nereide Stela Santos Magalhães
Mariane Cajubá de Britto Lira Nogueira
机构
[1] Universidade Federal de Pernambuco (UFPE),Laboratório de Imunopatologia Keizo
[2] Av. Prof. Moraes Rego,Asami (LIKA)
[3] Centro Acadêmico de Vitória,Laboratório de Nanotecnologia, Biotecnologia e Cultura de Células
[4] Universidade Federal de Pernambuco (CAV/UFPE),undefined
来源
Journal of Nanoparticle Research | 2022年 / 24卷
关键词
COVID-19; Nanomedicine; Nanocarriers; Liposomes; Nanoparticles;
D O I
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学科分类号
摘要
The pandemic COVID-19 has worried everyone due to the high mortality rate and the high number of people hospitalized with severe acute respiratory syndrome caused by SARS-CoV-2. Given the seriousness of this disease, several companies and research institutions have sought alternative treatment and/or prevention methods for COVID-19. Due to its versatility, nanotechnology has allowed the development of protective equipment and vaccines to prevent the disease and reduce the number of severe COVID-19 cases. Thus, this article combined the main works and products developed in a nanotechnological field for COVID-19. We performed a literature search using the keywords “COVID-19,” “SARS-CoV-2,” “nanoparticles,” “nanotechnology,” and “liposomes” in the SciELO, Scifinder, PubMed, Sciencedirect, ClinicalTrials, and Nanotechnology Products databases Database. The data survey indicated 48 articles, 62 products, and 32 patents. The use of nanotechnology against COVID-19 has brought benefits in several parameters of this disease, helping develop rapid diagnostic tests that release the result in 10 min, as well as developing vaccines containing genetic material from SARS-CoV-2 (DNA, mRNA, and protein subunits). Nanotechnology is an exceptional ally against COVID-19, contributing to the most diverse areas, helping both prevent, diagnose, and treat COVID-19.
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[1]  
Almeida DS(2020)Biodegradable CA/CPB electrospun nanofibers for efficient retention of airborne nanoparticles Process Saf Environ Prot 144 177-185
[2]  
Martins LD(2019)Nanoparticles in the clinic: an update Bioengineering & Translational Medicine 4 e10143-2387
[3]  
Muniz EC(2021)SARS-CoV-2: insight in genome structure, pathogenesis and viral receptor binding analysis – an updated review Int Immunopharmacol 95 107493-7782
[4]  
Rudke AP(2016)Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date Pharm Res 33 2373-82
[5]  
Squizzato R(2016)Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 9 e1416-2954
[6]  
Beal A(2020)Nano research for COVID-19 ACS Nano 17 7760-292
[7]  
Anselmo AC(2020)Nanotechnology for COVID-19: therapeutics and vaccine research ACS Nano 21 73-2017
[8]  
Mitragotri S(2021)Viral targets for vaccines against COVID-19 Nat Rev Immunol 184 2939-334
[9]  
Bhat EA(2021)Antibody evasion by the P.1 strain of SARS-CoV-2 Cell 325 276-126
[10]  
Khan J(2020)Scope and limitations on aerosol drug delivery for the treatment of infectious respiratory diseases J Control Release 8 1985-639