Early detection of prostate cancer in German urological practice by digital rectal examination and prostate-specific antigen [Fruherkennung des Prostatakarzinoms in der urologischen Praxis mit digitaler rektaler Untersuchung und prostataspezifischem antigen]

被引：0

作者：

Luboldt H.-J. ^{[1
]}

Hüsing J. ^{[1
]}

Altwein J.E. ^{[1
]}

Bichler K.-H. ^{[1
]}

Czaja D. ^{[1
]}

Fornara P. ^{[1
]}

Jöckel K.-H. ^{[1
]}

Schalkhäuser K. ^{[1
]}

Weißbach L. ^{[1
]}

Wirth M. ^{[1
]}

Rübben H. ^{[1
]}

机构：

[1] Urologische Klinik und Poliklinik, Institut für Medizinische Informatik, Universität-GH-Essen

来源：

Der Urologe A | 2000年 / 39卷 / 4期

关键词：

Early detection; Positive predictive value; Prostate cancer; PSA;

D O I：

10.1007/s001200050365

中图分类号：

学科分类号：

摘要：

For the early detection of prostate cancer, a patient should undergo digital rectal examination (DRE) and PSA investigation. Follow-up of increased PSA levels detects nearly 80% of cancers. Positive predictive value of suspicious DRE and PSA is about 50%. Whereas in the first evaluation of this case-finding trial about 70% of the patients had organ-confined cancers, nearly all of the detected cancers in the follow-up investigation were organ confined. The increased number of organ-confined cancers detected in early periodical examinations can lead to a reduction of mortality and morbidity from prostate cancer.

引用

页码：330 / 333

页数：3

共 11 条

[1]

Altwein, J.E., Luboldt, H.J., Results of a screening program in Germany for early detection of early prostate cancer (1999) Prostate Cancer Prostatic Dis 2, (SUPPL. 2), pp. 15-18

[2]

Carter, H., Epstein, J., Chan, D., Fozard, J., Pearson, J., Recommended prostate-specific antigen testing intervals for the detection of curable prostate cancer (1997) JAMA, 277, pp. 1456-1462

[3]

Carter, H.B., Landis, P.K., Metter, E.J., Prostate-specific antigen testing of older men (1999) J Natl Cancer Inst, 91, pp. 1733-1737

[4]

Cooner, W.H., Mosley, B.R., Rutherford C.L., Jr., Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen (1990) J Urol, 143, pp. 1146-1152

[5]

Feuer, E.J., Merrill, R.M., Hankey, B.F., Cancer surveillance series: Interpreting trends in prostate cancer - Part II: Cause of death misclassification and the recent rise and fall in prostate cancer mortality (1999) J Natl Cancer Inst, 91, pp. 1025-1032

[6]

Hoedemaeker, R.F., Kranse, R., Rietbergen, J.B., Evaluation of prostate needle biopsies in a population-based screening study (1999) Cancer, 85, pp. 145-152

[7]

Hodge, K., McNeal, J., Terris, M., Stamey, T., Random systematic versus directed ultrasound guided core biopsies of the prostate (1989) J Urol, 142, pp. 74-80

[8]

Holzel, D., Klamert, A., Schmidt, M., (1995), pp. S361-S372. , 5.30 Prostatakarzinom - ICD 185.Zuckschwerdt, Muenchen

[9]

Luboldt, H.-J., Altwein, J.E., Bichler, K.-H., Fruherkennung des Prostatakarzinoms-Erste Ergebnisse einer prospektiven multizentrischen Studie in Deutschland (1999) Urologe A, 38, pp. 114-123

[10]

Schroder, F.H., Kranse, R., Rietbergen, J., Hoedemaeker, R., Kirkels, W., The European Randomized Study of Screening for Prostate Cancer (ERSPC): Members of the ERSPC, Section Rotterdam (1999) Eur Urol, 35, pp. 539-543

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