Human induced pluripotent stem cells differentiate into insulin-producing cells able to engraft in vivo

[1] Barton FB(2012)Improvement in outcomes of clinical islet transplantation: 1999–2010 Diabetes Care 35 1436-1445

[2] Rickels MR(2012)Update on islet transplantation Cold Spring Harb Perspect Med 2 a007823-1401

[3] Alejandro R(2006)Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells Nat Biotechnol 24 1392-1953

[4] McCall M(2007)Generation of insulin-producing islet-like clusters from human embryonic stem cells Stem Cells 25 1940-344

[5] Shapiro AMJ(2007)In vitro derivation of functional insulin-producing cells from human embryonic stem cells Cell Res 17 333-578

[6] D’Amour KA(2007)Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage Stem Cells Dev 16 561-265

[7] Bang AG(2009)A small molecule that directs differentiation of human ESCs into the pancreatic lineage Nat Chem Biol 5 258-871

[8] Eliazer S(2011)Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells Development 138 861-371

[9] Jiang J(2012)The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells Diabetologia 55 358-2029

[10] Au M(2012)Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice Diabetes 61 2016-2442

[1] Barton FB(2012)Improvement in outcomes of clinical islet transplantation: 1999–2010 Diabetes Care 35 1436-1445

[2] Rickels MR(2012)Update on islet transplantation Cold Spring Harb Perspect Med 2 a007823-1401

[3] Alejandro R(2006)Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells Nat Biotechnol 24 1392-1953

[4] McCall M(2007)Generation of insulin-producing islet-like clusters from human embryonic stem cells Stem Cells 25 1940-344

[5] Shapiro AMJ(2007)In vitro derivation of functional insulin-producing cells from human embryonic stem cells Cell Res 17 333-578

[6] D’Amour KA(2007)Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage Stem Cells Dev 16 561-265

[7] Bang AG(2009)A small molecule that directs differentiation of human ESCs into the pancreatic lineage Nat Chem Biol 5 258-871

[8] Eliazer S(2011)Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells Development 138 861-371

[9] Jiang J(2012)The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells Diabetologia 55 358-2029

[10] Au M(2012)Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice Diabetes 61 2016-2442