Randomized controlled study of gemcitabine plus S-1 combination chemotherapy versus gemcitabine for unresectable pancreatic cancer

被引:0
作者
Kentaro Sudo
Takeshi Ishihara
Nobuto Hirata
Fumiaki Ozawa
Tadashi Ohshima
Ryosaku Azemoto
Kenji Shimura
Takeshi Nihei
Takayoshi Nishino
Akihiko Nakagawa
Kazuyoshi Nakamura
Taro Hara
Motohisa Tada
Rintaro Mikata
Katsunobu Tawada
Osamu Yokosuka
So Nakaji
Taketo Yamaguchi
机构
[1] Chiba Cancer Center,Department of Gastroenterology
[2] Chiba University,Department of Gastroenterology and Nephrology, Graduate School of Medicine
[3] Kameda Medical Center,Department of Gastroenterology
[4] Saitama Medical University,Department of Hepato
[5] Saitama Red Cross Hospital,biliary
[6] Kimitsu Chuo Hospital,pancreatic Surgery, Saitama Medical Center
[7] Asahi General Hospital,Department of Gastroenterology
[8] Mito Saiseikai General Hospital,Department of Gastroenterology
[9] Tokyo Women’s Medical University Yachiyo Medical Center,Department of Gastroenterology
[10] Numazu City Hospital,Department of Internal Medicine
来源
Cancer Chemotherapy and Pharmacology | 2014年 / 73卷
关键词
Pancreatic cancer; S-1; Gemcitabine; Randomized controlled study;
D O I
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学科分类号
摘要
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页码:389 / 396
页数:7
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[1]  
Burris HA(1997)Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial J Clin Oncol 15 2403-2413
[2]  
Moore MJ(2007)Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group J Clin Oncol 25 1960-1966
[3]  
Andersen J(2011)FOLFIRINOX vs gemcitabine for metastatic pancreatic cancer N Engl J Med 364 1817-1825
[4]  
Green MR(1996)Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators Anticancer Drugs 7 548-557
[5]  
Rothenberg ML(1987)Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts Jpn J Cancer Res 78 748-755
[6]  
Modiano MR(1993)Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats Cancer Res 53 4004-4009
[7]  
Cripps MC(2008)A late phase II study of S-1 for metastatic pancreatic cancer Cancer Chemother Pharmacol 61 615-621
[8]  
Portenoy RK(2009)A phase II study of S-1 in gemcitabine-refractory metastatic pancreatic cancer Cancer Chemother Pharmacol 63 313-319
[9]  
Storniolo AM(2011)Phase II study of S-1 in patients with gemcitabine-resistant advanced pancreatic cancer Cancer Chemother Pharmacol 67 249-254
[10]  
Tarassoff P(2011)Phase II study of oral S-1 and concurrent radiotherapy in patients with unresectable locally advanced pancreatic cancer Int J Radiat Oncol Biol Phys 80 119-125